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Upcoming CVD outcome trials, such as the EXSCEL study of exenatide weekly, the LEADER study of liraglutide and the REWIND study of dulaglutide might provide further insight in this matter (Table 1)
People at highest risk of deficiency include individuals with pernicious anemia, individuals with gastrointestinal disorders or surgery, breast-fed infants of vegan mothers, individuals following a vegan or vegetarian diet, and the elderly
GLP-1 receptor agonists are synthetic medications that bind to the same cellular receptors as this natural hormone, amplifying these appetite-suppressing and blood-sugar-regulating effects